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PPIs have been tested against placebo for silent reflux (LPR) in randomized trials. A meta-analysis of 8 placebo-controlled trials (344 patients) found PPIs did not reduce throat symptoms significantly more than placebo. A later review of the RCTs reached the same conclusion. PPIs lower stomach acid. LPR symptoms in the throat involve more than acid, including pepsin and a barrier that is not holding pressure. That may be why acid suppression alone so often falls short. If you take a prescribed
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PPIs have been tested against placebo for silent reflux (LPR) in randomized trials. A meta-analysis of 8 placebo-controlled trials (344 patients) found PPIs did not reduce throat symptoms significantly more than placebo. A later review of the RCTs reached the same conclusion. PPIs lower stomach acid. LPR symptoms in the throat involve more than acid, including pepsin and a barrier that is not holding pressure. That may be why acid suppression alone so often falls short. If you take a prescribed
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Part 7 ~ Every Screen Resolution Explained Every screen resolution explained, from 144p to 16K — what the numbers really mean and how much resolution you actually need. What is 1080p, 1440p or 4K, and why can a phone look sharper than a giant TV? We go through 144p, 240p, 360p, 480p, 720p, 1080p, 1440p, ultrawide 21:9, 4K, 5K and 8K: pixel counts, pixel density (PPI), progressive vs interlaced, why QHD is called
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