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3:58
YouTube
Charagh Academy
MicroRNA (miRNA) biogenesis and mode of action
Briefly, a miRNA gene (MIR gene), is transcribed into long single stranded preliminary-miRNA (pri-miRNA) transcript with the help of RNA polymerase II (RNA Pol II) in the nucleus. The pri-miRNA is converted into stem loop structure called precursor-miRNA (pre-miRNA), which is stabilized by the DAWDLE (DDL) enzyme. The Dicer-like 1 (DCL1), with ...
2.5K views
Jul 4, 2021
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