Perhaps the showpiece game of the opening weekend pits Arsenal against Manchester United, a game that was once a title decider, now pitting second from last season against 15th. It does not get much easier for the Gunners from their on out with their 38 game league campaign seeing two of their toughest away games in their first six.

Liverpool will host Manchester United at Anfield on October 25 in Gameweek 8 of the 2025/26 Premier League. The English archrivals will then meet at Old Trafford on May 2, 2026, in Gameweek 35.

Champions Liverpool host Bournemouth in the season’s first match while Arsenal travel to Old Trafford to play Man Utd.