Figure 3: Recovery of the epsin layer and of the complete lattice after dehydration. The amplified DNA was subcloned into pETBlue 1 (Novagen), excised with Bam HI and Hind III, and then inserted into ...

Asynaptic levels of the protein clathrin are a determinant factor for synaptic plasticity of neurons, researchers have shown. Neurons transmit information in a specialized contact points called ...

Clathrin mediated endocytosis (CME) at pre-synaptic terminals is functionally coupled to neuro-transmitter release. Like other cytosolic proteins, clathrin is synthesized in cell-bodies and conveyed ...

After it fills with cargo, the pit pinches off to form a clathrin-coated, membrane-bound vesicle inside the cell, which then proceeds to its proper destination. In cultured cells, hundreds of these ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 11 (May 23, 2000), pp. 6120-6125 (6 pages) The GTPase dynamin I is required for synaptic vesicle (SV) ...

This study is reported by Hualan Chen’s group from the State Key Laboratory for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences.

This is a preview. Log in through your library . Abstract The clathrin-coated pit lattice is held onto the plasma membrane by an integral membrane protein that binds the clathrin AP-2 subunit with ...

Clathrin coated pits (CCPs) are spherical, cage-like structures located on the plasma membrane that are responsible for receptor-mediated endocytosis. CCPs bud off the cell membrane with their ...

The paper S. Kaur et al., “An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis,” eLife, 3:e00829, 2014. For decades, scientists observed clathrin-mediated ...

Cells have a clever way called clathrin-mediated endocytosis to transport cargos like growth factors across the cell membrane and into the cell. Researchers used a sophisticated fluorescence ...

Researchers of the group of cellular and molecular neurobiology of the Bellvitge Biomedical Research Institute (IDIBELL) and the University of Barcelona, led by researcher Artur Llobet, have shown ...