San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

There’s no reason for the 49ers to deviate from Monday’s game plan. If the Vikings, with their dynamic, chaotic defense, can ...

The San Francisco 49ers offense takes another hit. Wide receiver Deebo Samuel is expected to miss “a couple weeks” after ...

San Francisco 49ers receiver Deebo suffered a calf strain that should sideline him for "a couple of weeks," according to ...

San Francisco 49ers head coach Kyle Shanahan believes Deebo Samuel would be a stellar running back in the NFL.

The Cardinals' Drew Petzing unlocked Marvin Harrison Jr., and Matt LaFleur successfully steered the Packers without Jordan ...

Christian McCaffrey's calf and Achilles injuries continues to linger as the team considers placing him on injured reserve.

Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have ...

Looking at Sunday’s San Francisco 49ers at LA Rams Week 3 NFL odds, lines and trends. Here’s what you need to know.

The Los Angeles Rams host the San Francisco 49ers on Sunday as both NFC West rivals try to shake off dismal Week 2 ...

The retirement of Aaron Donald has shifted the landscape, pushing both the 49ers and Rams to adapt their strategies for an ...