A team of scientists has identified an enzyme called PurF as a new drug target for tuberculosis, offering a fresh line of ...

Researchers from Imperial and the London School of Hygiene & Tropical Medicine (LSHTM) have discovered a drug target that ...

Background Gut bacteria have been implicated in a wide range of health conditions, yet their potential role in preventing and treating muscle-wasting disorders remains largely unexplored. Objective We ...

Many people associate high uric acid with heavy meals, red meat, or alcohol. So when a routine blood test suddenly shows ...

Xanthine oxidoreductase (XOR) catalyzes the final steps of purine catabolism: the oxidation of hypoxanthine to xanthine, and xanthine to UA. XOR exists as interconvertible proteoforms, xanthine ...

Lifting heavy weights and hitting your daily protein goal isn’t just a surefire way to build sculpted muscles—it can also help increase your metabolism. And while it may seem like metabolism only ...

Scientists from Duke-NUS Medical School and their international collaborators have developed a new computational tool that maps how gene pathways interact in complex biological systems. Using this ...

NUDT5 enzyme acts as a molecular scaffold that maintains metabolic balance. Inside every cell, a finely tuned metabolic network determines when to build, recycle or stop producing essential molecules.

Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...