Complementary biochemical and structural findings reveal molecular principles underlying substrate selectivity by a model hyaluronan synthase.

When many disease-causing bacteria encounter penicillin, they are not always destroyed right away, shifting into a temporary survival state called ...

Nucleotide synthesis—the production of the basic components of DNA and RNA—is essential for cell growth and division. In most animal cells, this process depends closely on properly functioning ...

Nucleotide synthesis-the production of the basic components of DNA and RNA-is essential for cell growth and division. In most animal cells, this process depends closely on properly functioning ...

The findings, published in Nature Metabolism, open a new path toward future treatments for severe mitochondrial diseases that currently have no cure Nucleotide synthesis—the production of the basic ...

While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...

Inosine, a basic component of purine nucleotide, is mainly seen only as a building block in nucleotide synthesis. It is also a versatile bioactive molecule with diverse biofunctions. These ...

How This Fits Into Industry Trends The broader biotech industry is moving in two directions: refining chemical synthesis while also exploring enzymatic synthesis. Enzymatic approaches, using ...