Background GPR171 suppresses T cell immune responses involved in antitumour immunity, while its role in inflammatory bowel disease (IBD) pathogenesis remains unclear. Objective We aimed to investigate ...

Background and aims Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance because SI is a driver of the most severe forms of ADC, including ...

Chronic liver disease is a cluster of disorders associated with complex haemodynamic alterations, which is characterised by structural and functional disruptions of the intrahepatic and extrahepatic ...

Objective Biological therapies and small molecules continue to be evaluated in moderate to severely active ulcerative colitis, but are often studied in placebo-controlled trials, meaning their ...

Department of Medicine 1, University of Erlangen-Nuremberg, Erlangen, Germany Correspondence to Dr Christoph Becker, 1. Department of Medicine, University of Erlangen-Nuremberg, Hartmannstrasse 14, 91 ...

Correspondence to Professor Min Dai, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing ...

Laboratory for Enteric Neuroscience (LENS), TARGID, KU Leuven, Leuven, Belgium Correspondence to Professor Pieter Vanden Berghe, Laboratory for Enteric Neuroscience (LENS), TARGID, KU Leuven, O&N 1 ...

Dr J Tibble, Department of Gastroenterology, King’s College School Medicine and Dentistry, Bessemer Road, London SE5 9PJ, UK. BACKGROUND The diagnosis of non-steroidal anti-inflammatory drug (NSAID) ...

Objective To characterise gut microbiome in patients with hepatocellular carcinoma (HCC) and evaluate the potential of microbiome as non-invasive biomarkers for HCC. Design We collected 486 faecal ...

Objective To develop an interpretable artificial intelligence algorithm to rule out normal large bowel endoscopic biopsies, saving pathologist resources and helping with early diagnosis. Design A ...