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Ginger for the treatment and prevention of migraine headaches: a systematic review and meta-analysis of randomised controlled trials

Objective To determine the efficacy of ginger (either stand-alone or as an adjunct treatment) for the treatment and management of migraine headaches. Methods We searched PubMed, Embase, CINAHL, ...
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Adapt or die: how the pandemic made the shift from EBM to EBM+ more urgent

Evidence-based medicine (EBM’s) traditional methods, especially randomised controlled trials (RCTs) and meta-analyses, along with risk-of-bias tools and checklists, have contributed significantly to ...
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Is a one-size-fits-all ‘12-month rule’ appropriate when it comes to the last search date in systematic reviews?

Correspondence to Dr Gillian Stokes, Social Research Institute, EPPI Centre, University College London, London, WC1H 0NS, UK; gillian.stokes{at}ucl.ac.uk Searches conducted a year or more before ...
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Balancing benefits and potential risks of vaccination: the precautionary principle and the law of unintended consequences

Vaccination is a life-saving endeavour, yet risk and uncertainty are unavoidable in science and medicine. Vaccination remains contentious in the public mind, and vaccine hesitancy is a serious public ...
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Twenty-one years of the International Shared Decision Making Conference: lessons learnt and future priorities

Correspondence to Dr Natalie Joseph-Williams, Wales Centre for Primary and Emergency Care Research, Cardiff University, Cardiff, CF10 3AT, UK; josephnj1{at}cardiff.ac.uk The first International Shared ...
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How effective are ‘age’ tools at changing patient behaviour? A rapid review

Correspondence to Dr Bavidra Kulendrarajah, Centre for Evidence-Based Medicine, Oxford University, Oxford OX1 2JD, UK; bavidra10{at}gmail.com Background A common form of risk communication is to relay ...
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Meta-analysis using individual participant data from randomised trials: opportunities and limitations created by access to raw data

Correspondence to Ewelina Rogozińska, Women’s Health Research Unit, Barts and the London School of Medicine and Dentistry, Queen Mary University London, London E1 2AB, UK; e.a.rogozinska{at}qmul.ac.uk ...
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BMJ Evidence Based Medicine – Deputy Editor Vacancy

Role Advertisement: Deputy Editor Application deadline: 13th November 2026 Start date: Dependant on availability BMJ is seeking an enthusiastic and collaborative Deputy Editor to join the editorial ...
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Table 3

Missing—impute, NIHSS score—continuous, OTT—continuous 794 1.25 (0.91 to 1.73) 0.173 Missing—impute, NIHSS score—continuous, OTT—categorical 794 1.33 (0.96 to 1.85) 0.086 Missing—impute, NIHSS ...
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Applying the estimand framework to safety: aligning estimators with treatment effects in the presence of intercurrent events

Understanding the risks associated with healthcare interventions is essential for clinical decision-making and for the regulatory evaluation of new drugs. Yet, safety analyses in randomised controlled ...
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Defining and interpreting the clinical relevance of intervention effects for patient-reported outcomes: the smallest worthwhile effect construct

In clinical research, statistically significant effects do not necessarily indicate that an intervention provides benefits that are meaningful to patients. This is particularly important for ...
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Educating health professionals in evidence-based practice in 2026

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...