TEL AVIV, Israel (AP) — Iran fired a new wave of missile attacks on Israel early Monday, killing at least five people, while Israel claimed in the fourth day of the conflict that it had now achieved “aerial superiority” over Tehran and could fly over the Iranian capital without facing major threats.

The United States advised Americans not to travel to Israel after another wave of Iranian missile attacks struck the country.

Israel expanded its attacks on Iran on Monday, striking the headquarters of state television after ordering residents to leave part of Tehran, as the fiercest and deadliest confrontation in the history of the Israeli-Iranian conflict entered its fourth day.

At least 224 people have been killed in Iran by Israeli strikes, Netanyahu's office said on Monday. The Israel Defense Forces issued a warning to residents in District 3 of Tehran to "immediately leave" ahead of planned strikes there.

The Iranian regime faces pressure as Israel strikes military targets, with Iranian Americans advocating for the overthrow of what one Iranian American describes as a "paper tiger regime."

TREY YINGST, FOX NEWS: 65 total missiles were fired at Israel overnight. The Israelis struck back, killing the head of Iran's intelligence agency and his deputy. The Israelis also say they have taken out one-third of ballistic missile launchers.

Israel struck buildings in Tehran belonging to the Islamic Republic of Iran Broadcasting, or IRIB, Iran's state-owned media company, with the blasts seemingly heard live on television hours after the Israeli military said residents and workers in that part of the capital should leave.

Israel warned Tehran civilians to evacuate the city ahead of planned Israeli strikes on “the Iranian regime’s military infrastructure” on Monday—the first time in the now four-day conflict that an evacuation warning has been issued for targeted residential areas.

Petah Tikva, in central Israel, suffered some of the worst damage after Iran fired a huge wave of ballistic missiles overnight.

Israeli President Isaac Herzog joins 'America's Newsroom' to discuss the latest escalation with Iran.