Until about 20 years ago, systemic treatment options for moderate/severe psoriasis were limited and nonspecific. To get an idea of how much the field has changed, clinical guidelines on psoriasis ...

Please provide your email address to receive an email when new articles are posted on . Compared with methotrexate, systemic therapies for psoriasis either reduced or slightly increased cardiovascular ...

Half of patients exposed to placebo in clinical trials experienced adverse events (AEs), which may be partially explainable by nocebo effects, according to a recent review and meta-analysis. Half of ...

Patients with psoriasis often have comorbidities that are linked to the systemic inflammation of psoriasis and its treatment, according to study findings published in The Journal of Dermatology. The ...

CMO, discussed a presentation from Maui Derm 2026 in which he spoke about therapies in the pipeline for psoriasis.

The initial choice of an oral nonbiologic systemic therapy for patients with psoriasis is often driven by insurance requirements; patients often must try and fail treatment with an older therapy ...

Older adults with severe or refractory psoriatic disease face a unique challenge: Balancing the need for effective systemic treatment with the increased risk for serious infections. A cohort study ...

Low-grade systemic inflammation, indicated by elevated levels of systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and C-reactive protein (CRP), was associated with a ...

Psoriasis, a chronic autoimmune condition, causes inflammation in the skin, most often leading to thick, scaly areas called plaques. An overactive immune system speeds up skin cell development, ...

Like other inflammatory conditions, psoriasis often comes with concurrent systemic comorbidities, and physicians should be aware of symptoms that suggest associated conditions. Comorbidities include ...

Topical treatments, such as ointments, creams, lotions, and sprays, are often the first-line treatment for people with psoriasis. As psoriasis progresses or becomes more severe, though, topical ...