New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Two new studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature Structural ...

Early in the development of sperm, a strange event happens: the X and Y chromosomes condense into tight packages and are sequestered away from the other 44 human chromosomes. If any part of this ...

In a study published in Cell Research, a research team has, for the first time, resolved the high-resolution in situ structure of the central apparatus (CA) within the axoneme of mammalian sperm. CA ...

Gene expression related to fertilization, sperm motility, and sperm structure in the testes of Tle6 -deficient mice showed an overall increase. Together, the findings of this study highlighted the ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

Researchers from The University of Osaka find that CFAP91 and EFCAB5 proteins are crucial for sperm motility, and that loss of function of either of these proteins reduces male fertility in mice Osaka ...

A Utah biotech startup says it has grown functional human sperm in a lab and used it to create early embryos—a development that, if validated, could dramatically expand options for men with severe ...

Researchers showed how what appears to be a tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature ...