Pemphigus is an autoimmune bullous disease, in which autoantibodies react with the cell–cell adhesion structures, desmosomes, causing blisters and erosions on the oral mucosa and skin. Pemphigus is ...

LONDON — The Belgian company Argenx said Wednesday that its closely watched antibody therapy failed to outperform placebo in a Phase 3 trial in an autoimmune condition that causes the skin to blister ...

Pemphigus, an autoimmune disease mediated by B cells and which causes painful blisters and sores on the skin and mucous membranes, is a rare chronic autoimmune condition that can be fatal if not ...

Sanofi SA’s high-profile phase III blow-up Sept. 9 with the oral BTK inhibitor rilzabrutinib in pemphigus brought fresh attention to the group of rare diseases – which cause blisters on the skin and ...

An autoimmune blistering disease of the mucous membranes and skin, pemphigus vulgaris (PV) derives its name from the Greek word, pemphix, for blister. 1 PV is characteristically seen in older patients ...

Pemphigus is a rare autoimmune blistering disease involving the skin and mucous epithelia. It is clinically characterized by flaccid blisters and erosions (Figure 1) and, if left untreated, could be ...

A phase 3 trial explored which treatment option for pemphigus vulgaris, a rare skin disease, resulted in better outcomes after 52 weeks. In patients with pemphigus vulgaris, rituximab was superior to ...

Kaye Kent eats oatmeal or Cream of Wheat for breakfast most mornings. If she actually liked hot cereal it wouldn’t be so bad, but she doesn’t have a choice. She can’t eat anything harder than bread ...