As the calendar turns to October and the leaves begin to change, the action across the NFL is ramping up in a big way. In Week 5, there are a number of notable matchups, including the first game of this year's London slate,

Preview the Week 5 matchup between the Detroit Lions and Cincinnati Bengals with predictions, odds, over/under, spread, betting lines and more.

The No. 3 Miami Hurricanes and No. 19 Florida State Seminoles meet Saturday at Doak Campbell Stadium. Kickoff is scheduled for 7:30 p.m. ET.

The Badgers had another disappointing loss in Week 4, struggling on both sides of the ball in a 27-10 defeat to the Maryland Terrapins. It was seen as a must-win game for the Badgers, given how tough the team’s schedule is the rest of the way, but Wisconsin squandered the big opportunity and dropped to 2-2.

Preview the Week 5 matchup between the Los Angeles Chargers and Washington Commanders with predictions, odds, over/under, spread, betting lines and more.

Alabama has played the part of a Top 10 team since their Week 1 loss to Florida State. Plagued by slow starts under second-year Head Coach Kalen DeBoer, the Crimson Tide jumped Georgia at the start last weekend in Athens and won a hard-fought and crucial SEC clash in Athens, 24-21.

This game will feature two great running backs, with Kyren Williams and Christian McCaffrey looking like two of the league's true bellcow ball carriers through the first month of the season. Williams is listed as high as -185 in the latest NFL anytime touchdown scorer odds,