Elevated interferon levels are independently linked to key metabolic abnormalities in SLE, including dyslipidemia and pancreatic β‑cell dysfunction.
Interferon receptor knockout chickens uncover how type I and III interferons differentially shape avian antiviral immunity and influenza disease outcomes.
In a new study, researchers from Johns Hopkins Medicine say they have uncovered insights as to why lupus symptoms and severity present differently in individuals with the autoimmune condition, which ...
Due to differences in clinical presentation and limited knowledge, diagnosing Sjögren's disease in children can be challenging. Although dysregulation of multiple immune response pathways has been ...
In a recent study published in The New England Journal of Medicine, researchers used the TOGETHER platform trial protocol to perform a phase III randomized controlled trial (RCT) to evaluate the ...
Early interferon therapy reduces secondary myelofibrosis risk in young ET and PV patients. Cytoreductive drugs do not lower thrombotic event risk in young patients. Elevated white blood cell counts ...
Interferon signal reprograms macrophage mitochondria to promote inflammation resolution, finds study
When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. But it is just as important to resolve that inflammation and return ...
In 1980, TIME Magazine wrote about interferon as the “if” drug for cancer. Promising studies sparked widespread hope around the potential of the interferon to treat cancer, only if it could deliver ...
A new drug quashes all coronavirus variants. But regulatory hurdles and a lack of funding make it unlikely to reach the U.S. market anytime soon. By Benjamin Mueller Over the past year, America’s ...
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