From synthetic chromosomes and recoded genomes to next-generation gene therapies and engineered cells, discover how genome-scale engineering is redefining the possibilities of biology while reshaping ...

More than two decades after scientists announced the completion of the first human genome sequence, the human genome ...

The human genome is an easy place to get lost. Only 2% of its three billion letters encode proteins, and the rest is diabolically hard to decipher. An artificial-intelligence-generated ‘atlas’ of the ...

A new review argues that host chromatin architecture and three-dimensional genome rewiring, not just HPV oncoproteins, ...

Sequencing nearly half a million genomes, researchers show that most additive genetic influences on height, lipids, and other complex traits are now directly measurable, while pinpointing ultra-rare ...

The history of genomics has long been a story of reading a book where only every fiftieth page made sense. While the Human Genome Project gave us the full sequence of human DNA over two decades ago, ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the known number of potential regulatory elements in the genome to 2.37 million, ...

Join us as we travel back in time. We have arrived in the Devonian period, some 420 to 360 million years ago. In a shallow area near the water's edge, something happened that would forever change life ...

Many repetitive regions of the genome have been considered "junk DNA" because the available technologies did not allow them to be studied at sufficient resolution. This is the case for the SST1/NBL2 ...

Most bacteria live outside human cells. Mycoplasma penetrans does not. Instead, it inserts a spear-like structure into a ...