The evaluation of new drugs designed to treat specific anemias should include a thorough understanding of underlying pathophysiology, with a focus on enhancing oxygen transport. In this concise review ...

The process consists of multiple overlapping steps, including blood flow, diffusion of oxygen, chemical reactions inside cells, and oxygen uptake by tissues. As these processes occur simultaneously ...

The base unit of the body are cells, and cells require energy. As tissues and organs become more complex, the utilities that ensure their metabolic demands are met increase in capacity and ...

Assessment of microcirculatory functional capacity is considered to be of prime importance for therapy guidance and outcome prediction in critically ill intensive care patients. Here, we show ...

Schematic of how individual red blood cells (RBCs) carry oxygen through capillaries to oxygenate tissues. The team found that RBCs can regulate how much oxygen is released in tissues, wherein ...