In this article, ACROBiosystems discusses how the complement cascade and it's various components could potentially be leveraged for therapeutic potential in COVID-19, cancer and general inflammation.

Unlike traditional therapies that broadly inhibit complement activation, hitting this target could preserve the anti-microbial functions of complement, while specifically inhibiting this harmful ...

Continued activation of complement system damages tissue and blood cells The researchers followed 113 COVID-19 patients for up to one year after their acute SARS-CoV-2 infection and compared them ...

Although all anti-O2-antigen antibodies enabled activation of the complement system, anti-capsule antibodies were less effective in their stimulation and ability to to form hexameric IgG clusters.

Increased activation of the complement pathway and terminal complement complex formation in 6-month long COVID patients could lead to tissue damage.

We are studying the role of the complement system in kidneys and brains during health and disease. Traditionally, major complement proteins were shown to be generated by the liver and are functional ...

“Nipocalimab appears to have an effect on lowering but not completely suppressing complement activation, and may thus potentially reduce NMJ damage, while still allowing the complement pathway ...

Continued activation of complement system damages tissue and blood cells The researchers followed 113 COVID-19 patients for up to one year after their acute SARS-CoV-2 infection and compared them ...